Children’s Trust began its work on adverse childhood experiences (ACEs) with the idea that a shared understanding of the impact of traumatic events in the lives of children could lead to the prevention of poor health and social outcomes as adults. That idea quickly blossomed into a statewide ACE Initiative that involves training, collecting and disseminating data, building a prevention planning framework, and promoting sound legislative policy. At the 2016 ACE Summit that brought together national and state experts with 300 attendees, we discussed what it will take to lead community-based efforts to address and prevent interrelated and intergenerational health and social problems.